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pentobarbital will minimize the extent or impact of nateglinide by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can cut down panobinostat amounts by ~70% and cause treatment failur

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